Imperial College London

The Cross-Faculty NMR Centre at Imperial College is specialised in screening of biological macromolecule and elucidation of detailed structural, dynamic and functional properties of biological complexes. The facility hosts 800, 600, and 400 MHz spectrometers.

Contacts:
Prof. Steve Matthews

Dr. Yingqi xu

NMR Equipment

Very-High Field (700-800 MHz)

Bruker Avance III HD 800 MHz standard bore NMR spectrometer equipped with SampleJet for 5 mm (550 μl) and 3 mm (170 μl) NMR tubes, with capacity of up to 30 positions for tubes with spinners and five positions for NMR tube racks (up to 480 sample tubes in total). This is normally equipped with the cryoprobe but can switch to probes for 31P, 19F when needed.

Solution state probes:

  • 5 mm 1H-optimised triple resonance (1H, 13C, 15N, 2H TCI) He-cooled cryoprobe, z-gradient, T: -40°C to +80°C, automated tuning and matching
  • 5 mm quadrupole resonance (1H, 31P, 13C, 15N, 2H QXI ) probe, z-gradient, T: -40°C to +80°C
  • 5 mm PASEI (1H, 19F) probe, optimised for 1H and 19F detection, z-gradient, T: -40°C to +80°C

High Field (600 MHz)

600 MHz standard bore NMR spectrometer equipped with 5mm TCI cryoprobe and InsightMR Flowunit, 3.2 mm HCN triple resonance CPMAS probe (maximum MAS frequency 20 kHz) and 1.3 mm HCN triple resonance CPMAS probe (maximum MAS frequency 67 kHz).

Additional capabilities

400 MHz Jeol standard bore NMR spectrometer with auto sample changer and 5 mm HFX probe (auto tuning)