University of Liverpool
The NMR Centre for structural biology located in the Institute of Integrative Biology of University of Liverpool is specialised in biology, small molecules investigation and solid materials and operates with 600, 700 and 800 MHz spectrometers. The 800 MHz instrument operates in dual liquid-solid configuration on a 3-month rotation basis. It is mainly used for structural biology in liquid state NMR mode and in the field of inorganic materials chemistry in solid state NMR mode. The 700 MHz is dedicated to metabolomics applications.
Contacts:
Prof. Frédéric Blanc for solid state NMR
Dr. Marie Phelan for solution state NMR
NMR Equipment
Very-High Field (700-800 MHz)
Bruker Avance NEO 800 MHz narrow bore NMR spectrometer equipped with He-cooled cryoprobes and autosample changers SampleJet for 5 mm (550 μl), 3 mm (170 μl), 1.7 mm (37 μl) and 1 mm (8 μl) NMR tubes, with capacity of up to 96 positions for tubes without spinners (plus 3 positions for tubes with spinners) and five positions for NMR tube racks (up to 480 sample tubes in total).
Solution state probes:
- 5 mm 13C-optimised triple resonance (1H, 13C/15N, 2H TXO) cryoprobe, z-gradient, T: -40°C to +80°C, automated tuning and matching
- 5 mm 1H-optimised triple resonance (1H, 13C/15N, 2H TXI) cryoprobe, z-gradient, T: -40°C to +80°C, automated tuning and matching
- 5 mm X-optimised double resonance probe (109Ag-31P/1H/2H BBO), z-gradient, T: -150°C to +150°C, automated tuning and matching
Solid state probes
- 1.3 mm HX (31P-15N) double resonance MAS probe, maximum MAS frequency 67 kHz, T: -30°C to +70°C
- 1.9 mm HXY TriGamma triple resonance MAS probe with interchangeable inserts (see table below), maximum MAS frequency 42 kHz, T: -50°C to +80°C.
- 3.2 mm broadband X (31P-13C) single resonance MAS probe, maximum MAS frequency 24 kHz, T: -30°C to +70°C
- 3.2 mm HX low gamma (13C-183W) double resonance MAS probe, maximum MAS frequency 24 kHz, T: -30°C to +70°C
- 4 mm HR-MAS probe (1H/13C/2H), maximum MAS frequency 10 kHz, T: -20°C to +80°C
| X channel nucleus | Y channel nucleus |
|---|---|
| 31P | 29Si |
| 11B | 29Si, 17O |
| 23Na | 29Si, 17O |
| 27Al | 29Si, 17O |
| 13C | 2H, 17O, 15N |
Bruker Avance III HD 700 MHz narrow bore NMR spectrometer equipped with He-cooled cryoprobe and autosample changers SampleJet for 5 mm (550 μl), 3 mm (170 μl), 1.7 mm (37 μl) and 1 mm (8 μl) NMR tubes, with capacity of up to 96 positions for tubes without spinners (plus 3 positions for tubes with spinners) and five positions for NMR tube racks (up to 480 sample tubes in total). Provided with a 5 mm 1H-optimised triple resonance (1H, 13C, 15N, 2H TXI) cryoprobe, z-gradient, T: -40°C to +80°C, automated tuning and matching.
Additional capabilities
Lower-field instrumentation is available at the Department of Chemistry of the University of Liverpool.
Bruker Avance III HD 400 MHz wide bore NMR spectrometer equipped with a high-temperature 4 mm HX extended tuning range (31P-109Ag) double resonance MAS probe, maximum MAS frequency 10 kHz, T: 20°C to 400°C.