University of Cambridge

The University of Cambridge accommodates 2 NMR Facilities. The Biomolecular NMR Facility located in the Biochemistry Department has a wide range of expertise in solution NMR. Applications include structural and functional investigations of folded globular and membrane proteins, intrinsically disordered proteins, RNA and the study of macromolecular interactions. The facility hosts 3 spectrometers (800 MHz, 600 MHz and 500 MHz). The NMR Facility in the Department of Chemistry includes a 700 MHz spectrometer.

Contacts:

Professor Daniel Nietlispach (Biochemistry Department)

Dr. Peter Gierth (Chemistry Department)

NMR Equipment

Very-High Field (700-800 MHz)

800 MHz

Bruker Avance III 800 MHz narrow bore NMR spectrometer equipped with a 5 mm ¹H-optimised triple resonance (¹H, ¹³C, ¹⁵N, ²H TXI) He-cooled cryoprobe, z-gradient, T: 0°C to +80°C

700 MHz

Bruker Avance III 700 MHz narrow bore NMR Spectrometer for solution and solid-state experiments.

Solution state probe:

5 mm ¹³C-optimised triple resonance (¹H, ¹³C, ¹⁵N TXO) cryoprobe, z-gradient, T: -40°C to +150°C

Solid state probes:

1.3 mm HX (³¹P-¹⁵N) double resonance MAS probe, maximum MAS frequency 67 kHz, T: -30°C to +70°C
3.2 mm DVT MAS probe