University of Cambridge

The Biomolecular NMR Facility located in the Biochemistry Department of the University of Cambridge has a wide range of expertise in solution NMR. Applications include structural and functional investigations of folded globular and membrane proteins, intrinsically disordered proteins, RNA and the study of macromolecular interactions. The facility hosts a 800 MHz spectrometer; another very-high field spectrometer is located in the NMR facility of the Department of Chemistry.

Dr. Daniel Nietlispach (Biochemistry Department)

NMR Equipment

Very-High Field (700-800 MHz)

Bruker Avance III 800 MHz narrow bore NMR spectrometer equipped with a 5 mm 1H-optimised triple resonance (1H, 13C, 15N, 2H TXI) He-cooled cryoprobe, z-gradient, T: 0°C to  +80°C

Bruker Avance III 700 MHz narrow bore NMR Spectrometer for solution and solid-state experiments.

Solution state probe:

  • 5 mm 13C-optimised triple resonance (1H, 13C, 15N TXO) cryoprobe, z-gradient, T: -40°C to +150°C

Solid state probes:

  • 1.3 mm HX (31P-15N) double resonance MAS probe, maximum MAS frequency 67 kHz, T: -30°C to +70°C
  • 3.2 mm DVT MAS probe